As next-generation AI models rapidly evolve in scale, reasoning and multimodal capabilities, health systems will face new opportunities and new operational questions. This panel will explore how healthcare organizations can prepare for the next wave of AI advancement, including considerations around infrastructure, governance, workforce readiness and clinical integration. Panelists will discuss how leaders can evaluate emerging technologies while balancing innovation, security and long-term strategy. The conversation will also examine what health systems should prioritize today to remain adaptable as AI capabilities continue to accelerate.