The panel What It Takes to Advance Quality and Safety in 2025 & Beyond will focus on the evolving landscape of patient care and the strategies needed to improve quality and safety in the years ahead. Panelists will discuss the integration of emerging technologies, such as AI and predictive analytics, to enhance clinical decision-making and prevent errors. The session will explore the critical role of workforce training, leadership, and organizational culture in fostering a sustained commitment to safety and continuous improvement. Finally, experts will address how to navigate the challenges of regulatory changes, patient expectations, and financial pressures while maintaining the highest standards of care.