This session provides a comprehensive overview of various nurse-to-patient assignment strategies in infusion centers. It will explore the advantages of real-time assignment, such as enhanced nurse satisfaction, increased operational efficiency by minimizing wasted time, and smoother patient experiences. Key considerations for evaluating real-time assignment, including staff availability, physical space constraints, change management, and reliable workflows, will be discussed. For centers requiring pre-assignment, tools like iQueue can facilitate balanced assignments. The session delves into best practices for managing real-time assignments, encompassing strategic appointment scheduling based on staffing, staffing predictions, and thoughtful change management. Lastly, it introduces iQueue’s Patient Assignment tool, utilizing AI for instantaneous patient-nurse allocation, streamlining assignments without manual time and effort.